Thus, within reasonable limits of interpretation, current ATCC stocks of Dami carry at least 16 of 18 strulctural chromosome rearrangements (markers) identical to those originally reported by Dr Handin's laboratory. Given that Dami's original karyotype was determined a decade ago without the aid of modern FISH technology, the degree of cytogenetic correspondence is remarkable. By the same token, the cytogenetic identity of current and original stocks indicates that Dami had been supplanted by

HEL before the time of karyotyping, which was reportedly performed around July 19872year before Dami was deposited with the ATCC. Thus, any stocks of Dami obtained after July 1987 are likely to have been contaminated. Stocks obtained from Dr Handin's lab before this date might possibly contain original Dami cells and should be conserved to enable their identity to be checked by single-locus DNA fingerprinting, as original Dami stocks are no longer available from their originating laboratory due to loss after a freezer accident.
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Thus, within reasonable limits of interpretation, current ATCC stocks of Dami carry at least 16 of 18 structural chromosome rearrangements (markers) identical to those originally reported by Dr Handin's laboratory. Given that Dami's original karyotype was determined a decade ago without the aid of modern FISH technology, the degree of cytogenetic correspondence is remarkable. By the same token, the cytogenetic identity of current and original stocks indicates that Dami had been supplanted by
more

Thus, within reasonable limits of interpretation, current ATCC stocks of Dami carry at least 16 of 18 structural chromosome rearrangements (markers) identical to those originally reported by Dr Handin's laboratory. Given that Dami's original karyotype was determined a decade ago without the aid of modern FISH technology, the degree of cytogenetic correspondence is remarkable. By the same token, the cytogenetic identity of current and original stocks indicates that Dami had been supplanted by
more